The sister virus genus to marburg, the five strains of ebola are very similar. Cdc releases detailed history of the 20142016 ebola. Viral hemorrhagic fevers chapter 4 2020 yellow book. This book, the hot zone by richard preston, is a true account of the study of marburg and ebola viruses in the years preceding the full blown. This is a true account of the ebola outbreak that includes graphic descriptions of the horrors of this terrible virus. Virus ecology graphic communication resources ebola. Intensive education formal and informal approaches of the citizens of african can help prevent the spread. Thirty years of battling hot viruses around the world. Believed to have originated from reservoirs of the virus from the same kitum cave and also believed to have spread from bats to humans. Jan 10, 2020 ebola is the virus that causes ebola virus disease. Ebola virus can linger in semen of survivors for 9 months. The natural and human history of a deadly virus is a very interesting behindthescenes look at the quest to find the host animal carrying this devastating virus. Four of six known virus species of the ebolavirus genus are known to infect humans and cause ebola virus disease.
Chughtai, helping to solve the primary question of whats next and aiding in. The terrifying true story of the origins of the ebola virus by richard preston, ebola. Anyway, this one was written my glen closes of actress fame father who was a medical doctor in africa. Reston virus reston ebolavirus, known to cause disease in nonhuman. And, as a result of this book i have gained a more personal look at those who lost their lives to the first outbreak of ebola. Zaire ebola virus zebov, which was first identified in 1976, is the most virulent and the strain of the present epidemic in africa. This results in internal bleeding that can be lifethreatening. Researchers have long known that the ebola virus can linger in certain bodily fluids even after an infected person begins to recover.
Ebola virus, a rna virus, was discovered in 1976 as zaire ebolavirus and currently is responsible for outbreak in the west africa. The terrifying true story of the origins of the ebola. The figure above is a bar chart showing the number of cases of ebola viral disease evd in the ongoing outbreak that were reported from guinea, by week of symptom onset in during 2014. Like marburg, they cause hemorrhagic fever and are spread through contact with infected fluids. It is a severe, often fatal disease 50%90% fatality in humans and nonhuman primates such as monkeys, gorillas, and chimpanzees. Victim suffering from zaire ebola virus in the democratic republic of the congo. Ebola virus disease evd, or simply ebola, is a viral haemorrhagic fever of humans and other primates caused by ebolaviruses. The recent deadly outbreak in west africa 202016 was the largest in history, with 28,000 cases and 11,000. Ebola virus rna has been detected in breast milk up to 21 days after the onset of the disease and in vaginal secretions up to 33 days after onset.
The virus, named for the region in congo kinshasa where it. Feb, 2017 the story is well known among ebola experts the traditional healer who died from the virus in sierra leone and whose body infected mourners at her funeral, who in turn infected more than. The mucinliked region of the ebola virus envelope play a significant role in viral infection in nonhuman primates and. The diseases and disorders series offers young readers and researchers a means of understanding these ailments and their ramifications. A novel of the first outbreak, by a doctor who was there. In the current outbreak, an estimated 6070% of those infected have died, and in previous outbreaks the figure has reached almost 90%. Mar 27, 2014 the deadliest outbreak of ebola virus on record has sparked fears that the killer virus could spread from west africa to other regions and continents. Number of cases of ebola viral disease n 398, by week of symptom onset guinea, 2014 cases reported as of june 18, 2014. It is caused by an infection with one of five known ebola virus species, four of which can cause disease in people. A novel of the first outbreak, by a doctor who was there 9780804114325. It has a mortality rate of up to 85% without proper intravenous fluid replacement, but when supportive measures are given the mortality drops to about 50%. Ebola virus, ebola hemorrhagic fever, marburg hemorrhagic fever, marburg virus disease, filoviral.
This current manual gives an overview to management of ebola virus disease outbreaks from a practical point of view. The epidemic took a devastating toll on the people of west africa. But a new study shows that remnants of the virus remained in. Find all the books, read about the author, and more. It left a lasting impression and piqued my interest for the rest of my life. Ebola what to do is an ebook, which tells the history of ebola and how to treat it along with recommendations. Modeling the impact of interventions on an epidemic of ebola in sierra leone and liberia. Mar 17, 2015 ebola virus disease 202014 outbreak in west africa. The natural and human history of a deadly virus by david quammen ebola.
Ebola virus disease is a serious illness that causes viral hemorrhagic fever and is deadly in up to 90 percent of cases. The ebola virus causes the often fatal ebola virus disease evd previously known as ebola hemorrhagic fever. It is a tragedy, at rate at which ebola virus is spreading in west africa. Ebola is a rare but deadly virus that causes fever, body aches, and diarrhea, and sometimes bleeding inside and outside the body as the virus spreads through the body, it damages the immune. But the ongoing west african outbreak is the largest ebola virus disease outbreak in the history, world health organization who reported a total of 28,599 cases observed and 11,289 deaths from. The ebola virus is one of a number of viruses that cause a devastating disease in humans and closely related species such as monkeys, gorillas, and chimpanzees. Ebolavirus, genus of viruses in the family filoviridae, certain members of which are particularly fatal in humans and nonhuman primates. Ebola virus net outbreak news, diagnosis, prevention. Eleven cases were reported, including these four cases and seven cases medically evacuated from other countries. The story is well known among ebola experts the traditional healer who died from the virus in sierra leone and whose body infected mourners at her funeral, who in. In humans, ebolaviruses are responsible for ebola virus disease evd, an illness characterized primarily by fever, rash, vomiting, diarrhea, and hemorrhaging. Ebola virus and marburg virus have been cultured from ocular aqueous humor at 2 and 3 months after disease onset, respectively. Ebola virus disease, first recognized in 1976 in the democratic republic of the congo, is a serious and often fatal illness in humans and nonhuman primates.
The natural and human history of a deadly virus by. This gene creatively called the polymerase, or l is the largest one carried by the virus. Most strains of ebola hemorrhagic fever progresses quickly from the. Current and historical conditions indexed list of current and historical nationally notifiable conditions. Ebola is a rare and deadly disease caused by infection with a virus of the family filoviridae, genus ebolavirus.
Ebov, is one of six known species within the genus ebolavirus. This brief book is a product of sections of his 2012 book spillover and recent events. Structure of the ebola virus glycoprotein spike within the. Nov 04, 2014 ebola virus takes the alternative route. A virus consists of a core of nucleic acid, either rna or dna, surrounded by a coating of antigenic protein and sometimes a lipid layer surrounds it as well. Combined simian hemorrhagic fever and ebola virus infection in cynomolgus monkeys. The recent deadly outbreak in west africa 202016 was. The ailments and conditions that afflict people today can be confusing, disturbing, and painful emotionally as well as physically to impressionable young people. List of books and articles about ebola online research library. The disease ebola is caused by the ebola virus, which can be transmitted from person to person.
The virus, named for the region in congo kinshasa where it was first identified in 1976, emerged from the rain forest, where it survives in as yet unconfirmed hosts, possibly several species of fruit bats but potentially other mammal species. Ebola virus disease 202014 outbreak in west africa. This ebola book is more terrifying than fiction new york post. Ending it took an extraordinary international effort in which the u. Ebola virus disease is rare and represents a miniscule fraction of the major infectious diseases burden in africa.
David orenstein 4018631862 the viruses are masters of their attack, but researchers are working hard to fight them, said dr. From origins to outbreak covers ebola virus disease in its entirety from its origins through major outbreaks in the past to the present day outbreak. In march 2014, the largest ebola outbreak in history exploded across west africa. They are spread through direct contact with the bodily fluids of a sick person and can cause fever, headache, muscle pain. Ebola virus is a large concern of public and global health because it has such a high mortality rate that it is a very dangerous virus and a potential bioterrorism agent.
Ebola virus net is the web resource for anyone interested in ebola. Ebola ebola hemorrhagic fever, is a severe, often fatal disease in humans and nonhuman primates such as monkeys, gorillas, and chimpanzees. The journal published its first ebola article in 1995, volume 1, issue number 3. Ebola viruses ebovs cause periodic outbreaks of severe hemorrhagic disease 1. Ebola damages blood vessel walls and inhibits the blood from clotting. The terrifying true story of the origins of the ebola virus mass market paperback july 20, 1995. An aide reaches her bare hands inside the woman to deliver the stillborn baby, unaware that the virus has now invaded her body, too. Ebola virus disease evd is one of numerous viral hemorrhagic fevers.
International ebola virus crowdsourced information resource and community. Zaire ebolavirus, more commonly known as ebola virus i. Four of the six known ebolaviruses, including ebov, cause a severe and often fatal hemorrhagic fever in humans and other mammals, known as ebola virus disease evd. The ebola virus thats causing the devastating outbreak in west africa didnt even have a name just 38 years ago when it first surfaced and caused a mysterious illness among villagers in zaire. List of books and articles about ebola online research.
The disease is known as a hemorrhagic fever because of the massive internal bleeding caused by the viral infection. The ebola virus a virus is an ultramicroscopic infectious organism that, having no independent metabolic activity, can replicate only within a cell of another host organism. Rivers cm, lofgren et, marathe m, eubank s, lewis bl. Signs and symptoms typically start between two days and three weeks after contracting the virus with a fever, sore throat, muscular pain, and headaches. The basis of the book was prestons 1992 new yorker article crisis in the hot zone the filovirusesincluding ebola virus, sudan virus, marburg virus, and ravn virus are. Vomiting, diarrhoea and rash usually follow, along with decreased function of the liver and kidneys. April 4, 2014 perhaps no virus strikes as much fear in people as ebola.
Apr 11, 2017 ebola viruses ebovs cause periodic outbreaks of severe hemorrhagic disease 1. The deadliest outbreak of ebola virus on record has sparked fears that the killer virus could spread from west africa to other regions and continents. Ebola spotlight emerging infectious diseases journal cdc. It contains information on the west saharan response to ebola as well as highlights from the field in west africa from dr. In 2014, west african countries guinea, liberia, and sierra leone. As of november 14, 2014, the world health organization has reported a total of 21,296 ebola virus disease evd. This page includes the following topics and synonyms. However, its high casefatality rate, potential for humantohuman transmission and propensity to be associated with hospitalbased transmission is both concerning and a fertile source for hysteria 31,32. Four laboratoryconfirmed cases of ebola virus disease commonly known as ebola occurred in the united states in 2014. The 20142016 ebola epidemic was the first and largest epidemic of its kind, with widespread urban transmission and a massive death count of more than 11,300 people in guinea, liberia, and sierra leone.
The emerging infectious diseases journal has published many articles on ebola. An analysis of the epidemic spread and response orlando cenciarelli, 1, 2, stefano pietropaoli, 3 andrea malizia, 1, 2 mariachiara carestia, 1, 2 fabrizio damico, 1, 2 alessandro sassolini, 1, 2 daniele di giovanni, 1, 2 silvia rea, 2 valentina gabbarini, 2 annalaura. This part of the emedtv library covers the transmission, symptoms, and treatment of the virus, as well as the possibility of it being used for bioterrorism. Ebola virus is one of the most lethal viruses known.
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